UCSF adult and pediatric clinical trials

UCSF Brain Tumor Center Clinical Trials

Our clinical trials evaluate a broad range of innovative therapies for both adults and children with brain tumors. 

Identify Relevant Clinical Trials
Clinical Trial Phase
Intervention Model
Treatment Modality
Which of the following treatments has the patient already received?*
Genetic Features*
  • Recruiting Recruiting
  • Pediatrics Pediatrics
  • On Hold On Hold
Conditions
Glioma
Astrocytoma
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Atypical Teratoid / Rhaboid Tumor (AT/RT)
Ependymoma
Medulloblastoma
Pineal Region Tumors
This phase I clinical trial studies the side effects and best dose of pevonedistat when given together with irinotecan hydrochloride and temozolomide in treating patients with recurrent/refractory solid tumors (including CNS tumors) or lymphoma.
Recruiting
Conditions
Glioma
Astrocytoma
Glioblastoma (grade IV)
Anaplastic astrocytoma (grade III)
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Atypical Teratoid / Rhaboid Tumor (AT/RT)
Ependymoma
Medulloblastoma
Pineal Region Tumors
The purpose of this Phase I/II clinical trial is to evaluate the dosage, safety and efficacy of lenvatinib in combination with everolimus in treating pediatric patients with recurrent solid tumors, including central nervous system tumors.
Recruiting
Conditions
Glioma
Astrocytoma
Anaplastic astrocytoma (grade III)
Glioblastoma (grade IV)
Pleomorphic xanthoastrocytoma (grades II-III)
Ependymoma
Medulloblastoma
Oligodendroglioma
Pilocytic astrocytoma (grade I)
Atypical Teratoid / Rhaboid Tumor (AT/RT)
Brainstem Glioma
Diffuse Midline Glioma
Pineal Region Tumors
This phase II clinical trial tests the use of a precision medicine approach in treating pediatric patients with recurrent solid tumors, including central nervous system tumors. 
Recruiting
Conditions
Glioma
Astrocytoma
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Atypical Teratoid / Rhaboid Tumor (AT/RT)
Subependymal giant cell astrocytoma (grade I)
Choroid Plexus Tumors
Medulloblastoma
Pineal Region Tumors
The purpose of this Phase I clinical trial is to study the side effects and best dose of entinostat in treating pediatric patients with recurrent or refractory solid tumors.
Conditions
Medulloblastoma
Glioma
Astrocytoma
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Ependymoma
Metastatic Brain Tumor
Pineal Region Tumors
The purpose of this Phase I/II clinical trial is to study the side effects and best dose of irinotecan hydrochloride in combination with MK-1775 to treat pediatric patients with recurrent or refractory solid tumors.

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