UCSF adult and pediatric clinical trials

UCSF Brain Tumor Center Clinical Trials

Our clinical trials evaluate a broad range of innovative therapies for both adults and children with brain tumors. 

Identify Relevant Clinical Trials
Clinical Trial Phase
Intervention Model
Treatment Modality
Which of the following treatments has the patient already received?*
Genetic Features*
  • Recruiting Recruiting
  • Pediatrics Pediatrics
  • On Hold On Hold
Conditions
Glioma
Oligodendroglioma
Astrocytoma
Diffuse astrocytoma (grade II)
This clinical trial evaluates the safety and feasibility of a vaccine-based immunotherapy called GBM6-AD in patients with newly diagnosed or recurrent low-grade glioma. The vaccine contains glioblastoma lysate, which may help train patients' immune systems to recognize molecules made by glioma cells.
Recruiting
Conditions
Glioma
Astrocytoma
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Medulloblastoma
Choroid Plexus Tumors
Atypical Teratoid / Rhaboid Tumor (AT/RT)
The purpose is to evaluate cognitive, social, emotional, and behavioral functioning over time in patients already enrolled in a Children’s Oncology Group Phase III clinical trial.
Recruiting
Conditions
Glioma
Astrocytoma
Anaplastic astrocytoma (grade III)
Glioblastoma (grade IV)
Oligodendroglioma
This phase II clinical trial will evaluate the efficacy and safety of ONC201, an oral small molecule, in adult subjects with a recurrent H3 K27M-mutant glioma (grades III-IV).
Recruiting
Conditions
Glioma
Astrocytoma
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
Brainstem Glioma
Diffuse Midline Glioma
Atypical Teratoid / Rhaboid Tumor (AT/RT)
Ependymoma
Medulloblastoma
This phase I clinical trial studies the side effects and best dose of pevonedistat when given together with irinotecan hydrochloride and temozolomide in treating patients with recurrent/refractory solid tumors (including CNS tumors) or lymphoma.
Recruiting
Conditions
Glioma
Astrocytoma
Glioblastoma (grade IV)
This clinical trial will investigate the use of oncolytic polio/rhinovirus recombinant (PVSRIPO) alone or in combination with chemotherapy in adult patients with recurrent grade IV glioma.
Recruiting
Conditions
Glioma
Astrocytoma
Glioblastoma (grade IV)
Anaplastic astrocytoma (grade III)
Oligodendroglioma
Chemotherapy treatment of high grade gliomas (HGG), among other brain tumors, faces several challenges including the effective delivery of drugs to the tumor site. This clinical trial tests the combination of two different strategies for the delivery of a chemotherapy drug in patients with HGG.
Recruiting

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