Specialties: Brain and spinal tumors, including metastases
Dr. Golden is a radiation oncologist who specializes in treating tumors of the central nervous system, including primary brain and spinal tumors and tumors that have metastasized to the brain and spine. He is involved in multiple clinical trials with a focus on treating these types of tumors. He routinely uses various modalities of radiation oncology, including 3D conformal radiation therapy (3DCRT), intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), stereotactic radiosurgery (SRS), Gamma Knife, and CyberKnife.
Dr. Golden has helped to shape the new and evolving field of radiation and immunotherapy by showing how the use of radiation may contribute to a form of tumor cell death (immunogenic cell death) that can be utilized as a personalized anti-tumor vaccine. In addition, he is the lead author on the first clinical trial showing how local radiotherapy to a tumor in combination with immunotherapy can generate immune-mediated abscopal (from Latin ab-scopus, away from the target) responses in distant, non-irradiated, sites of disease that lead to improved patient survival.
Additionally Dr. Golden has conducted pre-clinical studies focused on the development of new treatments for patients with malignant gliomas. He was able to show that green tea polyphenols or chloroquine and its quinolone-based analogues may synergize with the cytotoxic effects of temozolomide, an FDA approved chemotherapy for glioblastoma.
2001: BS, Biology, University of Southern California
2009: MD, University of Southern California, Keck School of Medicine
2009: PhD, Pathobiology, University of Southern California, Keck School of Medicine
2009-1010: Intern, Neurosurgery, University of Chicago, Pritzker School of Medicine
2010-2014: Resident, Radiation Oncology, New York University, School of Medicine
2011-2012: Postdoctoral Fellow, Radiation Biology, New York University, School of Medicine
2014-2015: Clinical Instructor, Radiation Oncology, New York University, School of Medicine
2015-2017: Assistant Professor, Radiation Oncology, Cornell University, Weill Cornell Medical College
2017-Present: Assistant Professor, Radiation Oncology, UCSF
2015: Basic/Translational Science Abstract Award, American Society for Radiation Oncology
2012: NYU School of Medicine Excellence in Laboratory Research during Residency Award
2012: Scholar in Training Travel Award, Radiation Research Society
2011: Lynn Sage: Breast Cancer Achievement Award 2011: Competitive Research Fellowship Award, Chemotherapy Foundation