UCSF BTC Clinical Trials

Neuropsychological and Behavioral Testing in Younger Patients With Cancer


This observational study looks at neuropsychological (learning, remembering or thinking) and behavioral testing in younger patients with cancer. Collecting information over time from a series of tests may help doctors develop effective tests to measure neuropsychological and behavioral function of patients with cancer.

The purpose is to evaluate cognitive, social, emotional, and behavioral functioning over time in patients already enrolled in a Children’s Oncology Group Phase III clinical trial.

In this observational study, all eligible participants will complete a variety of tests at 9, 30, and 60 months post-diagnosis in a 1-hour session conducted by a neuropsychologist or psychologist. These include tests of intelligence, processing speed/attention, memory, language preference, general developmental progress, attention and behavior/social/emotional function, executive function, adoptive function, and quality of life. Additionally, parents complete a parent-report questionnaire to gather information about patient's function in terms of attention, memory, executive abilities, and behavioral, social, and emotional adaption.


Inclusion Criteria
  1. The patient must be currently be enrolled or plan to be enrolled on in a phase III Children’s Oncology Group therapeutic study that aims to examine neuropsychological, social, emotional, and/or behavioral functioning
  2. The patient must have receptive and expressive English language skills

For the most up-to-date list of criteria, please visit clinicaltrials.gov.

Exclusion Criteria
  1. Patients with a history of severe or profound mental retardation (i.e. intelligence quotient [IQ] =< 50) are not eligible for enrollment; PLEASE NOTE: Children with a prior history of attention deficit hyperactivity disorder (ADHD) or a specific learning disability (e.g. dyslexia) are eligible for this study

For the most up-to-date list of criteria, please visit clinicaltrials.gov.

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