Human Neurons at Birth, Alvarez-Buylla Lab

Developmental Biology

Understanding the basic mechanisms underlying normal developmental processes (like cell division, differentiation, and migration) in the brain can provide insight into how those same pathways are dysregulated or co-opted during tumorigenesis.

Some active areas of developmental biology research at UCSF include the following:

  • Mechanisms of adult neurogenesis and neuronal replacement
  • Signaling pathways and transcription factors regulating gliogenesis
  • Mechanisms underlying cell fate decision in oligodendrocyte precursor cells
  • Long non-coding RNA in neural development and glioma growth
  • Mechanisms of DNA repair in neural stem cells


The Labs