Chief, Pediatric Neurosurgery, UCSF Benioff Children's Hospital
Principal Investigator, Brain Tumor Center
Surgical Director, Pediatric Brain Center
Specialties: Pediatric brain tumors, fetal myelomeningocele, hydrocephalus
Dr. Gupta is an expert in the evaluation and surgical management of neurological disorders in children, including conditions such as brain tumors, hydrocephalus, cranial and spinal congenital anomalies and vascular malformations.
Dr. Gupta's research interests include fundamental mechanisms of brain tumor progression and defining the biological response of tumors to various treatment strategies. Currently, his laboratory is focusing on cell-cell interactions during tumor progression, and the special role of pro-inflammatory cytokines. He is also involved in basic and translational research for brainstem glioma and medulloblastoma. He has a particular interest in drug delivery to the central nervous system and is surgical chair of a number of phase I studies conducted by the Pacific Pediatric Neuro-Oncology Consortium.
1987: MD, University of Toronto, Canada
1987-1988: Surgical Internship, Mount Sinai Hospital, Faculty of Medicine, University of Toronto
1988-1989: Residency, Neurosurgery, University of Ottawa, Canada
1989-1997: Residency, Neurosurgery, Department of Neurosurgery, University of Toronto
1991-1996: Research Fellow, Medical Research Council of Canada and Brain Tumor Center, Department of Neurological
1992-1996: PhD, Graduate Group in Biophysics, UCSF
1997-1998: Fellow in Pediatric Neurosurgery, Hospital for Sick Children, University of Toronto
1998-2000: Clinical Associate, Section of Neurosurgery, Department of Surgery, University of Chicago
2000-Present: Professor in Residence of Neurological Surgery and Pediatrics
2005: NIH/NINDS K08 Career Development Award
2004: SPORE Career Development Award, Department of Neurological Surgery, UCSF
2002: Hellman Family Award for Early Faculty, UCSF Cancer Center
1997: Alan Hudson Resident Teaching Award, Division of Neurosurgery, University of Toronto
1995: T.P. Morley Resident Research Award, Division of Neurosurgery, University of Toronto
1995: Junior Scientist Travel Award, International Congress of Radiation Research
1988: Outstanding Intern, Department of Emergency Medicine, Mount Sinai Hospital
1981: J.W. McConnell Scholarship, McGill University
New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model.
Louis N, Liu S, He X, Drummond DC, Noble CO, Goldman S, Mueller S, Bankiewicz K, Gupta N, Hashizume R.
J Neurooncol. 2018 Feb;136(3):475-484.
Pediatric high-grade glioma: biologically and clinically in need of new thinking.
Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, Phillips JJ, Simonds EF, Stafford JM, Tang Y, Pfister SM, Weiss WA.
Neuro Oncol. 2017 Feb 1;19(2):153-161.
Patient-derived Tumor Models for Diffuse Intrinsic Pontine Gliomas.
Hashizume R, Gupta N.
Curr Neuropharmacol. 2017;15(1):98-103. Review.