UCSF Brain Tumor Center Clinical Trials
Our clinical trials evaluate a broad range of innovative therapies for both adults and children with brain tumors.
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Recruiting
- Pediatrics
- On Hold
Conditions
Medulloblastoma
This phase II clinical trial will evaluate the efficacy of reduced craniospinal radiation therapy in combination with chemotherapy for patients with newly diagnosed WNT-driven medulloblastoma.
Conditions
Glioma
Astrocytoma
Anaplastic astrocytoma (grade III)
Glioblastoma (grade IV)
Pleomorphic xanthoastrocytoma (grades II-III)
Ependymoma
Medulloblastoma
Oligodendroglioma
Pilocytic astrocytoma (grade I)
Atypical Teratoid / Rhabdoid Tumor (AT/RT)
Brainstem Glioma
Diffuse Midline Glioma
Pineal Region Tumors
This phase II clinical trial tests the use of a precision medicine approach in treating pediatric patients with recurrent solid tumors, including central nervous system tumors.
Conditions
Glioma
Astrocytoma
Oligodendroglioma
Ependymoma
Diffuse astrocytoma (grade II)
Anaplastic astrocytoma (grade III)
Pleomorphic xanthoastrocytoma (grades II-III)
Pilocytic astrocytoma (grade I)
This is a pilot study to develop a liquid biomarker of hypermutation in glioma patients previously treated with the chemotherapy temozolomide.
Conditions
Glioma
Astrocytoma
Glioblastoma (grade IV)
Anaplastic astrocytoma (grade III)
Diffuse astrocytoma (grade II)
Chordoma
Schwannoma (grade 1)
Craniopharyngioma
Oligodendroglioma
Meningioma
Pituitary Tumor
This observational study will collect data to better understand our patient population and their behavior around cannabis, as well as clinical outcomes that might be linked to the consumption of cannabis.
Conditions
Glioma
This is a randomized, double-blind, placebo-controlled international phase III study in participants with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC201 following frontline radiotherapy extends overall survival and progression-free survival.
Conditions
Glioma
Astrocytoma
Anaplastic astrocytoma (grade III)
Diffuse astrocytoma (grade II)
Pleomorphic xanthoastrocytoma (grades II-III)
Ependymoma
Oligodendroglioma
This study will evaluate the feasibility and efficacy of various cognitive rehabilitation treatments in patients with grade II-III glioma.
Conditions
Glioma
Glioblastoma (grade IV)
This is a randomized, double-blind, placebo-controlled study designed to examine the impact of a custom-formulated, high CBD product on measures of anxiety, quality of life, and tumor progression and imaging stability in newly-diagnosed glioblastoma patients.
Conditions
Medulloblastoma
Atypical Teratoid / Rhabdoid Tumor (AT/RT)
This Phase I clinical trial will evaluate the safety and efficacy of MV-NIS, which is administered via injection into the tumor site or subarachnoid space, in treating children and young adults with recurrent medulloblastoma or AT/RT.